What's more important? To be right, or to be good? To be good, or to be great?
What are values? Are they an invention of the human mind? Or are they something that are part of the structure of the Universe? You know, some sort of cosmic order.
What is right, what is wrong? Are they entirely relative? Or, are there rights and wrongs that are absolute and unchangeable? If there are, how do we know them?
Do humans have inalienable rights? If they do, what about other species on this planet? Are animal rights "invented" by humans? If so, who gave us the right to presume that they didn't have any rights to start with?
Is man the measure of everything that's moral? What is morality? What is conscience? What is the difference between right and wrong? Is something that's not wrong right? Who determines it? Where do morality and conscience come from?
What is knowledge? What is belief? Are the two interchangeable? When you say you know something, what exactly do you mean? Is rationality the knower? How do you validate it? Is everything not a matter of belief (though there may be laws that explain things 99.99% of the time)?
Does God exist (I certainly believe so)? If so, how do we prove Its existence? Can it even be proved, in a way that will satisfy science (if not scientists)?
The questions go on and on, and I have no thoroughly convincing answers.